Khoa Le Anh Huynh

I'm a PhD Candidate in Biostatistics at Virginia Commonwealth Univeristy in Virginia, where I am working with Prof. Jinze Liu and Prof. Katarzyna M Tyc.

Before joining VCU, I earned my BS in Mathematics from University of Cincinnati (under the advice of Prof. Wang Xia). During my thesis work, I focused on developing expertise in generalized linear regression models and the least absolute shrinkage and selection operator (LASSO).

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Research

My professional interests primarily revolve around clustering, machine learning, optimization, and regression analysis. A significant portion of my research is dedicated to the development of specialized, automated tools for the preprocessing and analysis of complex, highly-multiplexed, and multimodal imaging data, particularly in single-cell studies. This includes work with advanced systems like PhenoCycler, MERSCOPE, and Xenium. In addition, I have been actively involved in harnessing the synergistic potential of methylation and fragmentomic signatures from blood-based circulating tumor DNA. By integrating these with multimodal deep-learning analyses, my work contributes to advancing early cancer detection methodologies.